SCHEMBL8411583

SCHEMBL8411583

CCN(CC)CCCNC(=O)CC(=O)NCCS

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
GAA P10253 1/20 0.50
LMNA P02545 3/20 0.46
PAOX Q6QHF9 1/20 0.44
DNM1 Q05193 1/20 0.44
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC9 Q9UKV0 2/20 0.40
HDAC5 Q9UQL6 2/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8411061 0.91 GAA (0.56) ALDH1A1GAALMNAPAOXDNM1
SCHEMBL8415048 0.83 DNM1 (0.56) ALDH1A1LMNAPAOXDNM1KDM4E
SCHEMBL18871047 0.83 DNM1 (0.54) ALDH1A1GAAPAOXDNM1HDAC3
SCHEMBL6033392 0.81 MEN1 (0.64) ALDH1A1GAALMNAPAOXDNM1
SCHEMBL11024881 0.79 ALDH1A1 (0.56) ALDH1A1GAALMNAPAOXDNM1
SCHEMBL5146559 0.79 ALDH1A1 (0.54) ALDH1A1GAALMNAPAOXDNM1
SCHEMBL8956368 0.77 ALDH1A1 (0.40) ALDH1A1GAALMNADNM1KDM4E
SCHEMBL7260964 0.77 ALDH1A1 (0.59) ALDH1A1GAALMNAPAOXKMT2A
SCHEMBL13655423 0.77 ALDH1A1 (0.59) ALDH1A1GAALMNAPAOXKDM4E
SCHEMBL24393605 0.76 DNM1 (0.35) ALDH1A1GAALMNADNM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935558-A FOR PERMANENT WAVING OF HAIR; IMPROVED CURLING, LOW ODOR L'OREAL, SA (FR) 1999-08-10 US claimed
EP-0653202-B1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent OREAL (FR) 1998-03-04 EP claimed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP claimed
US-5985257-A HAIR PERMANENT L'OREAL (FR) 1999-11-16 US disclosed
US-5935558-A FOR PERMANENT WAVING OF HAIR; IMPROVED CURLING, LOW ODOR L'OREAL, SA (FR) 1999-08-10 US disclosed
US-5843416-A Cosmetic composition containing an n-mercaptoalkylalkanediamide or one of its cosmetically acceptable salts as reducing agent L'OREAL (FR) 1998-12-01 US disclosed
EP-0653202-B1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent OREAL (FR) 1998-03-04 EP disclosed
US-5700454-A FOR PERMANENT WAVING OF HAIR WITH IMPROVED CURLING EFFICIENCY L'OREAL (FR) 1997-12-23 US disclosed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP disclosed