Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411680 | 0.91 | HDAC1 (0.47) | HDAC1HDAC6BRD4ALDH1A1HPGD | |
| SCHEMBL7565002 | 0.91 | OPRM1 (0.52) | HDAC1HDAC6ALDH1A1HPGDPKMYT1 | |
| SCHEMBL7572552 | 0.78 | MGAM (0.45) | HDAC1HDAC6ALDH1A1HPGDPKMYT1 | |
| SCHEMBL27415625 | 0.77 | PKMYT1 (0.52) | ALDH1A1HPGDPKMYT1SMN1; SMN2MAPT | |
| SCHEMBL7564998 | 0.75 | PKMYT1 (0.40) | ALDH1A1HPGDPKMYT1SMN1; SMN2MAPT | |
| SCHEMBL12086508 | 0.74 | HDAC1 (0.44) | HDAC1HDAC6ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2449556 | 0.73 | KDM4E (0.57) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL2442660 | 0.72 | KDM4E (0.56) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL8411708 | 0.72 | HDAC1 (0.60) | HDAC1HDAC6ALDH1A1HDAC3HDAC4 | |
| SCHEMBL7567057 | 0.72 | HDAC1 (0.71) | HDAC1HDAC6ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |