Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411682 | 0.91 | HDAC1 (0.56) | HDAC1HDAC6PKMYT1SMN1; SMN2MAPT | |
| SCHEMBL7565002 | 0.86 | OPRM1 (0.52) | HDAC1HDAC6PKMYT1SMN1; SMN2MAPT | |
| SCHEMBL8411706 | 0.75 | HDAC1 (0.49) | HDAC1HDAC6MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7572552 | 0.75 | MGAM (0.45) | HDAC1HDAC6PKMYT1SMN1; SMN2MAPT | |
| SCHEMBL8414466 | 0.74 | AOX1 (0.57) | HDAC1HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27415625 | 0.73 | PKMYT1 (0.52) | PKMYT1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL8411214 | 0.72 | RAD52 (0.70) | HDAC1HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7564998 | 0.72 | PKMYT1 (0.40) | PKMYT1SMN1; SMN2MAPTALDH1A1ATM | |
| SCHEMBL12086508 | 0.71 | HDAC1 (0.44) | HDAC1HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2449556 | 0.70 | KDM4E (0.57) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |