Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731753 | 0.87 | SRD5A2 (0.53) | SRD5A2 | |
| SCHEMBL10582748 | 0.85 | MBOAT4 (0.41) | SRD5A2SRD5A1 | |
| SCHEMBL7609106 | 0.85 | MBOAT4 (0.41) | SRD5A2SRD5A1 | |
| SCHEMBL10485581 | 0.84 | MBOAT4 (0.40) | SRD5A2 | |
| SCHEMBL9844548 | 0.82 | SRD5A2 (0.40) | SRD5A2 | |
| SCHEMBL8764680 | 0.81 | MBOAT4 (0.35) | SRD5A2SRD5A1 | |
| SCHEMBL9647692 | 0.80 | SRD5A2 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL4729968 | 0.79 | SRD5A1 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL5596628 | 0.79 | SRD5A1 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL6445820 | 0.78 | MBOAT4 (0.38) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377584-A | 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors | MERCK & CO., INC. (US) | 1983-03-22 | — | — | US | claimed |
| US-5914227-A | CULTURING TISSUE SAMPLE IN CONTROL MEDIA, WITH SUBSTRATE OF HORMONE SYNTHETASE, AND WITH SUBSTATE AND ENZYME INHIBITOR; MEASURING GROWTH AND DETERMINING PRESENCE OF HORMONE SYNTHETASE; FOR CLASSIFICATION AND APPROPRIATE TREATMENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0004949-B1 | 4-AZA-17-SUBSTITUTED-5-ALPHA-ANDROSTAN-3-ONE, THEIR A AND D HOMO ANALOGS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1983-09-21 | — | — | EP | disclosed |
| US-4377584-A | 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors | MERCK & CO., INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4220775-A | Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors | MERCK & CO., INC. (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0004949-A1 | 4-Aza-17-substituted-5-alpha-androstan-3-one, their A and D homo analogs, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1979-10-31 | — | — | EP | disclosed |