Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 9/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485958 | 0.89 | SRD5A2 (0.37) | SRD5A2SRD5A1LMNACYP3A4CYP2C9 | |
| SCHEMBL10485961 | 0.89 | SRD5A2 (0.37) | SRD5A2SRD5A1LMNACYP3A4CYP2C9 | |
| SCHEMBL7609106 | 0.85 | MBOAT4 (0.41) | SRD5A2SRD5A1MBOAT4GRIN1GRIN2B | |
| SCHEMBL10582748 | 0.85 | MBOAT4 (0.41) | SRD5A2SRD5A1MBOAT4GRIN1GRIN2B | |
| SCHEMBL10485581 | 0.84 | MBOAT4 (0.40) | SRD5A2MBOAT4GRIN1GRIN2B | |
| SCHEMBL8764680 | 0.82 | MBOAT4 (0.35) | SRD5A2SRD5A1MBOAT4GRIN1GRIN2B | |
| SCHEMBL9844548 | 0.82 | SRD5A2 (0.40) | SRD5A2MBOAT4GRIN1GRIN2B | |
| SCHEMBL4731753 | 0.80 | SRD5A2 (0.53) | SRD5A2MBOAT4GRIN1GRIN2B | |
| SCHEMBL8411683 | 0.80 | SRD5A2 (0.39) | SRD5A2SRD5A1 | |
| SCHEMBL9647695 | 0.76 | SRD5A2 (0.46) | SRD5A2SRD5A1LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116983-A | Azasteroids as intermediates | MERCK & CO., INC. (US) | 1992-05-26 | — | — | US | disclosed |