Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542343 | 1.00 | POLB (0.35) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL27934819 | 0.98 | POLB (0.34) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Carbon Monoxide SCHEMBL8744054 | 0.80 | HSP90AA1 (0.38) | POLBHSP90AA1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL27732427 | 0.77 | — | — | |
| SCHEMBL3276196 | 0.77 | GAA (0.38) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL2868301 | 0.77 | GAA (0.38) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL3391334 | 0.76 | POLB (0.35) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL539282 | 0.76 | POLB (0.35) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3337845 | 0.75 | GAA (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL175377 | 0.75 | POLB (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932664-A | Process for the production of hydrogenated ring-opened metathesis polymers | BAYER AG (DE) | 1999-08-03 | — | — | US | disclosed |