SCHEMBL539282

SCHEMBL539282

C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.Cl[Ru](Cl)=Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
HSP90AA1 P07900 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
IDO1 P14902 2/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3391334 1.00 POLB (0.35) POLBGAAHSP90AA1MAPK1SMN1; SMN2
SCHEMBL20787645 0.83 POLB (0.35) POLBGAAHSP90AA1MAPK1SMN1; SMN2
SCHEMBL29534779 0.80 TSHR (0.33) MAPTTSHR
SCHEMBL27768847 0.80 HSP90AA1 (0.38) POLBGAAHSP90AA1MAPK1SMN1; SMN2
SCHEMBL1005974 0.79 POLB (0.33) POLBGAAHSP90AA1MAPK1SMN1; SMN2
SCHEMBL995991 0.79 NPC1 (0.33) KDM4EHPGDALDH1A1TSHR
SCHEMBL29533582 0.79 ROCK2 (0.31)
SCHEMBL5573655 0.77 STS (0.30)
SCHEMBL4266302 0.77 ALDH1A1 (0.41) POLBMAPK1SMN1; SMN2MAPTALDH1A1
SCHEMBL2868301 0.77 GAA (0.38) POLBGAAHSP90AA1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179091-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-06-05 US claimed
CN-117264302-A Styrene butadiene rubber material for inner rubber layer of wear-resistant sand-absorbing rubber tube 蚌埠惠华管业有限公司 2023-12-22 CN claimed
WO-2022212752-A1 DEGRADABLE COPOLYMERS OF ENOL ETHERS WITH OLEFINIC MONOMERS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-10-06 WO claimed
EP-3634928-B1 METHOD OF INCREASING ALPHA-OLEFIN CONTENT LIQUIDPOWER SPECIALTY PRODUCTS INC (US) 2021-04-21 EP claimed
US-10973847-B2 Core-to-surface polymerization for the synthesis of star polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-04-13 US claimed
US-20200377652-A1 HIGH MOLECULAR WEIGHT POLYOXYALKYLENE WITH LOW GLASS TRANSITION TEMPERATURE, PRODUCED BY THE GRAFTING THROUGH METHOD COVESTRO DEUTSCHLAND AG (DE) 2020-12-03 US claimed
EP-1501784-B1 INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-03-13 EP claimed
US-9328108-B2 Process for preparing an intermediate of the macrocyclic protease inhibitor TMC 435 Janssen Pharmaceuticals, Inc. (US) 2016-05-03 US claimed
US-8981082-B2 Process for preparing an intermediate of the macrocyclic protease inhibitor TMC 435 Janssen Pharmaceuticals, Inc. (US) 2015-03-17 US claimed
US-20140235852-A1 PROCESS FOR PREPARING AN INTERMEDIATE OF THE MACROCYCLIC PROTEASE INHIBITOR TMC 435 Janssen Pharmaceuticals, Inc. (US) 2014-08-21 US claimed
WO-2003011298-A1 ANTIBACTERIAL OXAZINONES AND METHODS FOR THEIR USE AND SYNTHESIS CHIROLOGIX PHARMACEUTICALS INC. (CA) 2003-02-13 WO claimed
US-6476167-B2 REACTION PRODUCT OF: A CYCLIC OLEFIN MONOMER, WITH A CHAIN TRANSFER AGENT, IN PRESENCE OF A POLYMERIZATION CATALYST, WHEREIN THE FUNCTIONALITY OF OLEFIN DEFINED BY VAPOR PHASE OSMOMETRY AND TITRATION RANGES FROM 1.7 TO 2.2 BAYER CORPORATION 2002-11-05 US claimed
EP-1161460-A4 POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE ADVANCED POLYMER TECHNOLOGIES (US) 2002-04-17 EP claimed
EP-1088000-A4 POLYOLEFIN COMPOSITIONS HAVING VARIABLE TOUGHNESS AND/OR HARDNESS MATERIA INC (US) 2002-03-06 EP claimed
EP-1161460-A1 POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE Advanced Polymer Technologies, Inc. (US) 2001-12-12 EP claimed
US-6303837-B1 CYCLOOLEFINATION BY METATHESIS BAYER AKTIENGESELLSCHAFT (DE) 2001-10-16 US claimed
WO-2000046256-A9 POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE ADVANCED POLYMER TECHNOLOGIES (US) 2001-09-27 WO claimed
EP-1088000-A1 POLYOLEFIN COMPOSITIONS HAVING VARIABLE TOUGHNESS AND/OR HARDNESS Materia, Inc. (US) 2001-04-04 EP claimed
WO-2000046256-A1 POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE ADVANCED POLYMER TECHNOLOGIES, INC. (US) 2000-08-10 WO claimed
WO-1999060030-A1 POLYOLEFIN COMPOSITIONS HAVING VARIABLE TOUGHNESS AND/OR HARDNESS MATERIA, INC. (US) 1999-11-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10973847-B2 Core-to-surface polymerization for the synthesis of star polymers and uses thereof STARD7, MB, STARD3 POLB 1236/4885GAA 1708/4885HSP90AA1 3634/4885
US-20140235852-A1 PROCESS FOR PREPARING AN INTERMEDIATE OF THE MACROCYCLIC PROTEASE INHIBITOR TMC 435 CTRC, GTF3C4, CTSC POLB 1281/4885GAA 457/4885HSP90AA1 2734/4885
US-20250179091-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B POLB 3594/4885GAA 1503/4885HSP90AA1 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.