Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | GGH | Q92820 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411894 | 1.00 | FOLH1 (0.56) | FOLH1NAALAD2HTTALDH1A1MEN1 | |
| SCHEMBL28409358 | 0.88 | FOLH1 (0.55) | FOLH1NAALAD2HTTALDH1A1MME | |
| SCHEMBL28409360 | 0.88 | FOLH1 (0.55) | FOLH1NAALAD2HTTALDH1A1MME | |
| SCHEMBL21508983 | 0.80 | ALDH1A1 (0.41) | FOLH1HTTALDH1A1MEN1HPGD | |
| SCHEMBL27495948 | 0.80 | NAALAD2 (0.57) | FOLH1NAALAD2MAPK1GGT1GGH | |
| SCHEMBL27495949 | 0.80 | NAALAD2 (0.57) | FOLH1NAALAD2MAPK1GGT1GGH | |
| SCHEMBL23901605 | 0.80 | ALDH1A1 (0.54) | HTTALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL22750115 | 0.80 | FOLH1 (0.57) | FOLH1NAALAD2ALDH1A1MEN1HPGD | |
| SCHEMBL22750112 | 0.80 | FOLH1 (0.57) | FOLH1NAALAD2ALDH1A1MEN1HPGD | |
| SCHEMBL25485859 | 0.80 | FOLH1 (0.57) | FOLH1NAALAD2ALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |