SCHEMBL28409358

SCHEMBL28409358

O=C(O)CC[C@H](NCC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 9/20 0.55
NAALAD2 Q9Y3Q0 2/20 0.51
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MME P08473 1/20 0.47
ECE1 P42892 1/20 0.47
HTT P42858 1/20 0.46
GGH Q92820 1/20 0.45
CPA3 P15088 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28409360 1.00 FOLH1 (0.55) FOLH1NAALAD2ALDH1A1MAPK1L3MBTL1
SCHEMBL8411897 0.88 FOLH1 (0.56) FOLH1NAALAD2ALDH1A1MAPK1L3MBTL1
SCHEMBL8411894 0.88 FOLH1 (0.56) FOLH1NAALAD2ALDH1A1MAPK1L3MBTL1
SCHEMBL23747281 0.87 ALDH1A1 (0.49) FOLH1ALDH1A1MAPK1L3MBTL1
SCHEMBL8413844 0.86 CASP1 (0.51) FOLH1ALDH1A1MAPK1L3MBTL1MME
SCHEMBL8413850 0.86 CASP1 (0.51) FOLH1ALDH1A1MAPK1L3MBTL1MME
SCHEMBL21271490 0.84 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1GAA
SCHEMBL21271493 0.84 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1GAA
SCHEMBL21271491 0.84 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1GAA
SCHEMBL21555767 0.84 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400521-B Improved preparation method of 5R-benzyloxyaminopiperidine-2S-formate and oxalate thereof 新发药业有限公司 2020-05-08 CN claimed
CN-109400521-B Improved preparation method of 5R-benzyloxyaminopiperidine-2S-formate and oxalate thereof 新发药业有限公司 2020-05-08 CN disclosed