Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187480 | 0.97 | GRIK1 (0.41) | GRIK1GRIA4GRIK3GRIK5TDP1 | |
| Ammonia Solution, Strong SCHEMBL27555453 | 0.82 | ALDH1A1 (0.39) | FFAR3ALDH1A1 | |
| SCHEMBL1831176 | 0.82 | TDP1 (0.41) | GRIK1GRIA4GRIK3GRIK5TDP1 | |
| SCHEMBL8688580 | 0.82 | TDP1 (0.41) | GRIK1GRIA4GRIK3GRIK5TDP1 | |
| SCHEMBL1831174 | 0.82 | TDP1 (0.41) | GRIK1GRIA4GRIK3GRIK5TDP1 | |
| Ammonia Solution, Strong SCHEMBL20210811 | 0.80 | TDP1 (0.42) | GRIK1TDP1FFAR3ALDH1A1ALOX15 | |
| SCHEMBL28279159 | 0.79 | ALDH1A1 (0.40) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| Hydrochloric Acid SCHEMBL6937458 | 0.78 | TDP1 (0.40) | GRIK1TDP1FFAR3ALDH1A1ALOX15 | |
| SCHEMBL317482 | 0.77 | GRIK1 (0.36) | GRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL5253704 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866673-A | REACTING POLYAMIDE WITH A COMPOUND WHICH CONTAINS BOTH A POLYMERISABLE DOUBLE BOND AND AN OXIRANE RING, GRAFT POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-02 | — | — | US | disclosed |