Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049484 | 0.86 | CYP1A2 (0.42) | GRIK1GRIA4GRIK3GRIK5CYP1A2 | |
| SCHEMBL28279159 | 0.83 | ALDH1A1 (0.40) | GRIK1GRIA4GRIK3GRIK5CYP1A2 | |
| SCHEMBL26628967 | 0.82 | GABRR3 (0.32) | CYP1A2 | |
| SCHEMBL4592350 | 0.81 | GRIK1 (0.50) | GRIK1GRIA4GRIK3GRIK5CYP1A2 | |
| SCHEMBL28187480 | 0.79 | GRIK1 (0.41) | GRIK1GRIA4GRIK3GRIK5 | |
| Ammonia Solution, Strong SCHEMBL8411985 | 0.77 | GRIK1 (0.40) | GRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL6748978 | 0.77 | CYP1A2 (0.38) | CYP1A2PAOX | |
| SCHEMBL2329671 | 0.75 | PAOX (0.37) | GRIK1CYP1A2PAOX | |
| SCHEMBL1518639 | 0.74 | PAOX (0.38) | CYP1A2PAOX | |
| SCHEMBL4588094 | 0.74 | GRIK1 (0.32) | GRIK1GRIA4GRIK3GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1508042-A4 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | BIO RAD LABORATORIES (US) | 2008-04-02 | — | — | EP | claimed |
| EP-1508042-A2 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | Ciphergen Biosystems, Inc. (US) | 2005-02-23 | — | — | EP | claimed |
| US-20030218130-A1 | Biochips with surfaces coated with polysaccharide-based hydrogels | CIPHERGEN BIOSYSTEMS, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003093785-A2 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | CIPHERGEN BIOSYSTEMS, INC. (US) | 2003-11-13 | — | — | WO | claimed |
| US-12540348-B2 | Device and methods of using device for detection of aminoacidopathies | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2026-02-03 | — | — | US | disclosed |
| EP-3289353-B1 | DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA | UNIV MARYLAND (US) | 2024-09-25 | — | — | EP | disclosed |
| EP-2909606-B1 | DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES | UNIV MARYLAND (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-4139380-A1 | METHOD FOR PRODUCING A COLORED PLASTIC ARTICLE AND ARTICLE THEREOF | Smart Coloring GmbH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-4004137-A1 | LONG TERM REMOVABLE FILMS | Avery Dennison Corporation (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3901196-A1 | METHOD FOR PRODUCING A COLORED PLASTIC ARTICLE AND ARTICLE THEREOF | Smart Coloring GmbH (DE) | 2021-10-27 | — | — | EP | disclosed |
| EP-3540429-B1 | DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA | UNIV MARYLAND (US) | 2020-11-11 | — | — | EP | disclosed |
| US-10620187-B2 | Device and methods of using device for detection of hyperammonemia | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2020-04-14 | — | — | US | disclosed |
| WO-2014062985-A1 | DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES | UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2014-04-24 | — | — | WO | disclosed |
| US-8092993-B2 | Hydrogel thin film for use as a biosensor | NELLCOR PURITAN BENNETT LLC (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090170124-A1 | HYDROGEL THIN FILM FOR USE AS A BIOSENSOR | NELLCOR PURITAN BENNETT LLC (US) | 2009-07-02 | — | — | US | disclosed |
| EP-1508042-A4 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | BIO RAD LABORATORIES (US) | 2008-04-02 | — | — | EP | disclosed |
| US-20050153865-A1 | Cationically modified, anionic polyurethane dispersions | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | US | disclosed |
| EP-1508042-A2 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | Ciphergen Biosystems, Inc. (US) | 2005-02-23 | — | — | EP | disclosed |
| US-20030218130-A1 | Biochips with surfaces coated with polysaccharide-based hydrogels | CIPHERGEN BIOSYSTEMS, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003093785-A2 | BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS | CIPHERGEN BIOSYSTEMS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540348-B2 | Device and methods of using device for detection of aminoacidopathies | DAO, UROD, ALAD | GRIK1 2636/4885GRIA4 3884/4885GRIK3 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.