Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411227 | 0.82 | FFAR1 (0.37) | FFAR1KDM1AMAOBMAOAKMT2A | |
| SCHEMBL8410986 | 0.81 | S1PR5 (0.41) | FFAR1KDM1AMAOBMAOAKMT2A | |
| SCHEMBL8408803 | 0.80 | KCNH2 (0.44) | FFAR1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL8409277 | 0.79 | FFAR1 (0.39) | FFAR1KDM1AMAOBMAOAKMT2A | |
| SCHEMBL10477669 | 0.68 | MEN1 (0.50) | MAOBMAOAKMT2AMEN1GAA | |
| SCHEMBL5042093 | 0.67 | ALOX5 (0.55) | FFAR1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL31160636 | 0.67 | MEN1 (0.59) | FFAR1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL7811691 | 0.66 | ALOX5 (0.48) | — | |
| SCHEMBL21323277 | 0.66 | ALOX5 (0.47) | FFAR1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL8781522 | 0.65 | KCNH2 (0.44) | FFAR1MAOBMAOAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |