Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410986 | 0.92 | S1PR5 (0.41) | KCNH2RAB9AMAOBMEN1KMT2A | |
| SCHEMBL8411227 | 0.82 | FFAR1 (0.37) | KCNH2NPC1RAB9AMAOBOPRM1 | |
| SCHEMBL8409277 | 0.81 | FFAR1 (0.39) | KCNH2NPC1RAB9AMAOBMEN1 | |
| SCHEMBL8412154 | 0.80 | FFAR1 (0.35) | KCNH2MAOBMEN1KMT2AMAOA | |
| SCHEMBL8410875 | 0.78 | HCAR1 (0.32) | — | |
| SCHEMBL31624021 | 0.77 | KDM1A (0.45) | KCNH2NPC1RAB9AMAOBOPRK1 | |
| SCHEMBL31623869 | 0.76 | FFAR1 (0.39) | KCNH2NPC1RAB9AMAOBOPRM1 | |
| SCHEMBL8781522 | 0.76 | KCNH2 (0.44) | KCNH2NPC1RAB9AMAOBSCN3A | |
| SCHEMBL9940281 | 0.74 | TSHR (0.41) | KMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL8953741 | 0.73 | KMT2A (0.50) | MAOBMEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0787127-A1 | 5-LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011911-A1 | 5-LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1996-04-25 | — | — | WO | disclosed |