Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.75 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.75 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922134 | 0.94 | OPRD1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL8374709 | 0.94 | OPRD1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL14516215 | 0.94 | OPRD1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL149701 | 0.94 | OPRD1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Hydrochloric Acid SCHEMBL27503745 | 0.93 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Water SCHEMBL2443250 | 0.93 | OPRM1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082104 | 0.91 | OPRM1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL6755526 | 0.88 | OPRD1 (0.79) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL31424675 | 0.88 | OPRD1 (0.76) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082099 | 0.88 | OPRM1 (0.76) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908927-A | Synthesis of deuterated opiate glucuronides | HIGH STANDARD PRODUCTS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |