⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840959 | 0.88 | — | — | |
| SCHEMBL841268 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL14354909 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL12200469 | 0.72 | MMP8 (0.38) | — | |
| SCHEMBL14790935 | 0.70 | MMP8 (0.41) | — | |
| SCHEMBL12730654 | 0.70 | — | — | |
| SCHEMBL12363480 | 0.69 | MMP8 (0.35) | — | |
| SCHEMBL16811778 | 0.69 | MMP8 (0.35) | — | |
| SCHEMBL11913584 | 0.69 | MMP8 (0.35) | — | |
| SCHEMBL20100810 | 0.68 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8303819-B2 | Separation material | GAMBRO LUNDIA AB (SE) | 2012-11-06 | — | — | US | disclosed |
| US-20120160771-A1 | Separation Material | GAMBRO LUNDIA AB (SE) | 2012-06-28 | — | — | US | disclosed |
| US-8142844-B2 | Separating material | GAMBRO LUNDIA AB (SE) | 2012-03-27 | — | — | US | disclosed |