Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30996203 | 0.88 | CYP1A2 (0.55) | KMT2ACYP1A2CYP2D6MAPTLMNA | |
| SCHEMBL10448669 | 0.84 | KMT2A (0.51) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL9868831 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL8475420 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL14134758 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL19746373 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL8555578 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL8708894 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL9736812 | 0.82 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6MAPTHTT | |
| SCHEMBL6093583 | 0.82 | KMT2A (0.53) | KMT2ACYP1A2CYP2D6MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905148-A | Photochromic spirooxazine polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-05-18 | — | — | US | disclosed |
| US-5473068-A | Photochromic spirooxazine monomers and polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 1995-12-05 | — | — | US | disclosed |
| US-5322945-A | Photochromic spirooxazine monomers and polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1994-06-21 | — | — | US | disclosed |