Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 8/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810596 | 0.91 | PTGIR (0.46) | PTGIRPTGDRPTGS2 | |
| SCHEMBL8412775 | 0.87 | PTGIR (0.49) | PTGIRPTGDR | |
| SCHEMBL8809968 | 0.87 | PTGIR (0.59) | PTGIRPTGDR | |
| SCHEMBL8412021 | 0.82 | PTGIR (0.51) | PTGIRPTGDR | |
| SCHEMBL8411234 | 0.81 | PTGIR (0.46) | PTGIRPTGS2 | |
| SCHEMBL8412019 | 0.78 | PTGIR (0.65) | PTGIRPTGDR | |
| SCHEMBL8410517 | 0.76 | PTGIR (0.48) | PTGIR | |
| SCHEMBL8811301 | 0.72 | PTGIR (0.46) | PTGIRPTGS2 | |
| SCHEMBL8810297 | 0.72 | PTGIR (0.44) | PTGIRPTGDRPTGS2 | |
| SCHEMBL8413473 | 0.71 | PTGIR (0.76) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |