Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411234 | 0.91 | PTGIR (0.46) | PTGIRSIGMAR1PTGS2HTR1AADRA1A | |
| SCHEMBL8812547 | 0.91 | PTGIR (0.44) | PTGIRSIGMAR1PTGS2HTR1AADRA1A | |
| SCHEMBL8412769 | 0.88 | PTGIR (0.59) | PTGIRSIGMAR1PTGS2 | |
| SCHEMBL8411232 | 0.87 | PTGIR (0.49) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8810596 | 0.80 | PTGIR (0.46) | PTGIRPTGS2 | |
| SCHEMBL8414274 | 0.78 | SIGMAR1 (0.46) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8810160 | 0.76 | PTGIR (0.47) | PTGIRSIGMAR1HTR1AADRA1A | |
| SCHEMBL8808959 | 0.76 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8412021 | 0.75 | PTGIR (0.51) | PTGIR | |
| SCHEMBL8809395 | 0.74 | PTGIR (0.48) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |