Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810720 | 0.82 | PTGIR (0.59) | PTGIRTBXAS1TBXA2R | |
| SCHEMBL8414097 | 0.81 | PTGIR (0.58) | PTGIRTBXAS1TBXA2R | |
| SCHEMBL8410744 | 0.77 | TBXAS1 (0.58) | PTGIRTBXAS1 | |
| SCHEMBL8411186 | 0.77 | PTGIR (0.88) | PTGIRTBXAS1 | |
| SCHEMBL8811692 | 0.77 | PTGIR (0.41) | PTGIRTBXAS1 | |
| SCHEMBL8810220 | 0.77 | PTGIR (0.41) | PTGIRTBXAS1 | |
| SCHEMBL8412823 | 0.73 | HDAC1 (0.32) | PTGIR | |
| SCHEMBL8414276 | 0.72 | PTGIR (0.49) | PTGIRTBXA2R | |
| SCHEMBL8414332 | 0.72 | PTGIR (0.59) | PTGIRTBXA2R | |
| SCHEMBL8810723 | 0.71 | PTGIR (0.45) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |