Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414123 | 0.81 | C3AR1 (0.33) | PTGIRC3AR1 | |
| SCHEMBL8410755 | 0.78 | TBXAS1 (0.35) | HDAC1HDAC8HDAC6CFTRSLC6A2 | |
| SCHEMBL8411195 | 0.78 | PTGIR (0.45) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL8414280 | 0.74 | — | — | |
| SCHEMBL8412816 | 0.73 | PTGIR (0.53) | PTGIR | |
| SCHEMBL8414339 | 0.73 | PPARG (0.34) | PTGIR | |
| SCHEMBL8810720 | 0.72 | PTGIR (0.59) | PTGIR | |
| SCHEMBL8810723 | 0.72 | PTGIR (0.45) | HDAC1HDAC8HDAC6CFTRSLC6A2 | |
| SCHEMBL8413617 | 0.71 | HDAC1 (0.38) | HDAC1HDAC8HDAC6PTGIRC3AR1 | |
| SCHEMBL8410905 | 0.70 | PTGIR (0.49) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |