Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.89 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681240 | 0.94 | CASP1 (1.00) | CASP1SLC1A3SLC1A2SLC1A1ITGAV | |
| SCHEMBL5680708 | 0.78 | CASP1 (0.75) | CASP1SLC1A3SLC1A2SLC1A1ITGAV | |
| SCHEMBL8410540 | 0.77 | CASP1 (0.59) | CASP1L3MBTL1 | |
| SCHEMBL8413963 | 0.77 | CASP1 (0.68) | CASP1ITGAVATML3MBTL1ADAMTS4 | |
| SCHEMBL5681328 | 0.76 | CASP1 (0.78) | CASP1ATML3MBTL1ADAMTS4 | |
| SCHEMBL5680722 | 0.76 | CASP1 (0.67) | CASP1 | |
| SCHEMBL5683284 | 0.76 | CASP1 (0.47) | CASP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5678978 | 0.76 | CASP1 (0.70) | CASP1 | |
| SCHEMBL5680756 | 0.75 | CASP1 (0.66) | CASP1 | |
| SCHEMBL5678977 | 0.75 | CASP1 (0.71) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |