Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 3/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415046 | 0.87 | AOX1 (0.53) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL7567052 | 0.83 | HDAC1 (0.39) | RAD52HDAC1HDAC6KDM4ESMN1; SMN2 | |
| SCHEMBL7567055 | 0.77 | HDAC1 (0.54) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL8415065 | 0.76 | AOX1 (0.47) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL8415118 | 0.76 | RAD52 (0.40) | RAD52KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8411691 | 0.76 | MAPT (0.52) | RAD52AOX1KDM4EALDH1A1MAPT | |
| SCHEMBL7568211 | 0.76 | AOX1 (0.53) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL7565650 | 0.76 | AOX1 (0.53) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL8414249 | 0.76 | AOX1 (0.53) | RAD52AOX1UHRF1HDAC1HDAC6 | |
| SCHEMBL8414087 | 0.76 | AOX1 (0.46) | RAD52AOX1UHRF1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |