Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413848 | 0.85 | HRH3 (0.42) | KDM1AKCNH2MAOBCYP11B1CYP11B2 | |
| SCHEMBL28027502 | 0.75 | TSHR (0.38) | EPHX2 | |
| SCHEMBL25222944 | 0.73 | KDM1A (0.42) | KDM1AMAOBEPHX2ITKHRH3 | |
| SCHEMBL7392978 | 0.71 | DRD2 (0.36) | KDM1AKCNH2EPHX2 | |
| SCHEMBL7392980 | 0.71 | DRD2 (0.36) | KDM1AKCNH2EPHX2 | |
| SCHEMBL23987097 | 0.70 | EPHX2 (0.41) | KDM1AKCNH2MAOBEPHX2HRH3 | |
| SCHEMBL8910493 | 0.68 | DRD2 (0.37) | KDM1AHTT | |
| SCHEMBL7384878 | 0.68 | DRD2 (0.41) | KDM1ACYP11B1CYP11B2EPHX2 | |
| SCHEMBL7385405 | 0.68 | DRD2 (0.41) | KDM1ACYP11B1CYP11B2EPHX2 | |
| SCHEMBL7384873 | 0.68 | DRD2 (0.41) | KDM1ACYP11B1CYP11B2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |