Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385405 | 1.00 | DRD2 (0.41) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL7384878 | 1.00 | DRD2 (0.41) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL7392980 | 0.87 | DRD2 (0.36) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL7392978 | 0.87 | DRD2 (0.36) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL8910493 | 0.82 | DRD2 (0.37) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL8911065 | 0.79 | KDM1A (0.36) | DRD2TSHRKDM1ANPC1RAB9A | |
| SCHEMBL7388699 | 0.72 | CYP11B1 (0.43) | KDM1ARAB9AEPHX2CYP11B1CYP11B2 | |
| SCHEMBL8413848 | 0.70 | HRH3 (0.42) | KDM1AEPHX2CYP11B1CYP11B2 | |
| SCHEMBL7395422 | 0.70 | BRD4 (0.43) | RAB9ACYP11B1CYP11B2 | |
| SCHEMBL8413686 | 0.68 | KDM1A (0.41) | KDM1AEPHX2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |