Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408466 | 0.91 | GAA (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2704967 | 0.91 | GAA (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8380310 | 0.91 | GAA (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27870048 | 0.89 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8413227 | 0.88 | DGKA (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| Butane SCHEMBL5389100 | 0.87 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL243835 | 0.87 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5816004 | 0.86 | DGKA (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10901914 | 0.86 | CES2 (0.53) | ALDH1A1TSHRDGKATHRBFAAH | |
| SCHEMBL28203940 | 0.86 | DGKA (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490707-A1 | CATALYST MADE FROM AN ORGANIC COMPOUND AND USE THEREOF IN A HYDROPROCESSING AND/OR HYDROCRACKING METHOD | IFP Energies nouvelles (FR) | 2019-06-05 | — | — | EP | claimed |
| EP-3490707-A1 | CATALYST MADE FROM AN ORGANIC COMPOUND AND USE THEREOF IN A HYDROPROCESSING AND/OR HYDROCRACKING METHOD | IFP Energies nouvelles (FR) | 2019-06-05 | — | — | EP | disclosed |
| EP-0931820-A1 | Coating composition and its cured product | JSR Corporation (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5011848-A | Cardiovascular disorders, hypotensive agents | GLAXO, S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| US-4845109-A | VASODILATORS, HYPOTENSIVE AGENTS | MAKAROVA NATALYA V (SU) | 1989-07-04 | — | — | US | disclosed |
| US-4801599-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | GLAXO S.P.A. (IT) | 1989-01-31 | — | — | US | disclosed |
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| US-4352800-A | ANTIBIOTICS, BLOOD | KYOTO YAKUHIN KYOGO KABUSHIKI KAISHA (JP) | 1982-10-05 | — | — | US | disclosed |
| US-4277465-A | ENAMINE DERIVATIVE | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1981-07-07 | — | — | US | disclosed |
| US-4248873-A | Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
| EP-0009609-A2 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract, pharmaceutical composition comprising said adjuvant and process for preparing said pharmaceutical composition; enamine derivatives | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | disclosed |
| US-4166855-A | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ester, and its use as a peripheral vasodilator | BAYER AKTIENGESELLSCHAFT (DE) | 1979-09-04 | — | — | US | disclosed |
| US-3985758-A | 1,4-Dihydropyridine derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
| US-3932646-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS | FARBENFABRIKEN BAYER AG (DT) | 1976-01-13 | — | — | US | disclosed |
| US-3932645-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS | FARBENFABRIKEN BAYER AG (DT) | 1976-01-13 | — | — | US | disclosed |