Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15198025 | 1.00 | RAB9A (0.71) | RAB9AKDM4ENPC1SMN1; SMN2TOP2A | |
| SCHEMBL15192035 | 0.94 | RAB9A (0.61) | RAB9AKDM4ENPC1SMN1; SMN2TOP2A | |
| SCHEMBL10987585 | 0.94 | RAB9A (0.61) | RAB9AKDM4ENPC1SMN1; SMN2TOP2A | |
| SCHEMBL14953175 | 0.91 | RAB9A (0.68) | RAB9AKDM4ENPC1SMN1; SMN2TOP2A | |
| SCHEMBL12013755 | 0.86 | RAB9A (0.79) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL9212764 | 0.84 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL7159755 | 0.84 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL9216936 | 0.84 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL8413323 | 0.83 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL15074495 | 0.83 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690049-B1 | Agent for treating hepato biliary diseases | R TECH UENO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| EP-0690049-A2 | Agent for treating hepato biliary diseases | R-TECH UENO LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |