Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159755 | 1.00 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL9216936 | 1.00 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL15192035 | 0.89 | RAB9A (0.61) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL10987585 | 0.89 | RAB9A (0.61) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL9513278 | 0.86 | RAB9A (0.41) | RAB9AKDM4ENPC1SMN1; SMN2SMYD2 | |
| SCHEMBL8414209 | 0.84 | RAB9A (0.71) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL15198025 | 0.84 | RAB9A (0.71) | RAB9AKDM4ENPC1SMN1; SMN2RNASE1 | |
| SCHEMBL7161661 | 0.83 | RAB9A (0.40) | RAB9AKDM4ENPC1SMN1; SMN2SMYD2 | |
| SCHEMBL9213512 | 0.83 | RAB9A (0.40) | RAB9AKDM4ENPC1SMN1; SMN2SMYD2 | |
| SCHEMBL10447431 | 0.83 | RAB9A (0.40) | RAB9AKDM4ENPC1SMN1; SMN2SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541593-B1 | CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| EP-0541594-B1 | CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| US-5235072-A | 2-OXABICYCLO(2,2,1)HEPTANE DERIVATIVES AND PHARMACEUTICAL | SCHERING AKTIENGSELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0358290-B1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |
| WO-1992002495-A1 | CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN/BERGKAMEN (DE) | 1992-02-20 | — | — | WO | disclosed |
| WO-1992002494-A1 | CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN/BERGKAMEN (DE) | 1992-02-20 | — | — | WO | disclosed |