Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36180 | 0.97 | — | — | |
| SCHEMBL30365675 | 0.97 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL453052 | 0.97 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| Ammonia Solution, Strong SCHEMBL28243650 | 0.95 | — | — | |
| Propane SCHEMBL3445673 | 0.92 | THRB (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| Propane SCHEMBL15475973 | 0.92 | THRB (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| Methacrylic Acid SCHEMBL3300789 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL14054416 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL460181 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| Propanol SCHEMBL9487374 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5993972-A | Hydrophilic and hydrophobic polyether polyurethanes and uses therefor | TYNDALE PLAINS-HUNTER, LTD. (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0920467-A4 | HYDROPHILIC AND HYDROPHOBIC POLYETHER POLYURETHANES AND USES THEREFOR | TYNDALE PLAINS HUNTER LTD (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5962620-A | Hydrophicic and hydrophobic polyether polyurethanes and uses therefor | TYNDALE PLAINS-HUNTER, LTD. (US) | 1999-10-05 | — | — | US | disclosed |
| WO-1999047127-A1 | HYDROPHILIC AND HYDROPHOBIC POLYETHER POLYURETHANES AND USES THEREFOR | TYNDALE PLAINS-HUNTER, LTD. (US) | 1999-09-23 | — | — | WO | disclosed |
| EP-0920467-A1 | HYDROPHILIC AND HYDROPHOBIC POLYETHER POLYURETHANES AND USES THEREFOR | TYNDALE PLAINS-HUNTER, LTD. (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998008884-A1 | HYDROPHILIC AND HYDROPHOBIC POLYETHER POLYURETHANES AND USES THEREFOR | TYNDALE PLAINS-HUNTER, LTD. (US) | 1998-03-05 | — | — | WO | disclosed |