Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414273 | 0.88 | PTGIR (0.55) | SIGMAR1HTR1AADRA1APTGIR | |
| SCHEMBL8414277 | 0.81 | PTGIR (0.40) | SIGMAR1PTGIR | |
| SCHEMBL8811301 | 0.78 | PTGIR (0.46) | SIGMAR1HTR1AADRA1APTGIR | |
| SCHEMBL8809395 | 0.75 | PTGIR (0.48) | SIGMAR1PTGIR | |
| SCHEMBL8808959 | 0.75 | PTGIR (0.47) | SIGMAR1PTGIR | |
| SCHEMBL8410508 | 0.75 | PTGIR (0.44) | SIGMAR1PTGIR | |
| SCHEMBL8808628 | 0.73 | PTGIR (0.50) | SIGMAR1PTGIR | |
| SCHEMBL8411072 | 0.71 | PTGIR (0.78) | SIGMAR1HTR1AADRA1APTGIR | |
| SCHEMBL8811210 | 0.71 | PTGIR (0.44) | SIGMAR1PTGIR | |
| SCHEMBL8810160 | 0.70 | PTGIR (0.47) | SIGMAR1HTR1AADRA1APTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |