Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519368 | 0.85 | ABL1 (0.33) | ABL1ALPLALPIALPGRIN1 | |
| SCHEMBL8410501 | 0.83 | PTGIR (0.35) | ABL1ALPLALPIALPGRIN1 | |
| SCHEMBL8813614 | 0.66 | PTGIR (0.43) | PTGIRPTGDRPDE4B | |
| SCHEMBL8811346 | 0.66 | PTGIR (0.66) | PTGIRPTGDR | |
| SCHEMBL8812372 | 0.64 | PTGIR (0.59) | PTGIRPTGDRHTR7 | |
| SCHEMBL8520476 | 0.63 | PTGIR (0.64) | PTGIRPTGDR | |
| Hydrochloric Acid SCHEMBL9353386 | 0.57 | CARM1 (0.46) | CHRM1CHRM3CD274PTGER1PTGER4 | |
| SCHEMBL9353270 | 0.57 | CARM1 (0.46) | CHRM1CHRM3PTGER1PTGER4PTGER3 | |
| Hydrochloric Acid SCHEMBL9352963 | 0.57 | CARM1 (0.45) | CHRM1CHRM3PTGER1PTGER4PTGER3 | |
| SCHEMBL9890642 | 0.56 | CHRM1 (0.57) | CHRM1CHRM3PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |