Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738495 | 0.98 | MAPT (0.33) | MAPTHDAC8ALDH1A1MDM4TP53 | |
| SCHEMBL7461135 | 0.80 | TDP1 (0.38) | ALDH1A1 | |
| SCHEMBL13035644 | 0.77 | GABRA1 (0.41) | MAPT | |
| SCHEMBL18268986 | 0.77 | — | — | |
| SCHEMBL4394026 | 0.76 | MAPT (0.31) | MAPTHDAC8 | |
| SCHEMBL31201870 | 0.74 | GABRA1 (0.47) | ALDH1A1 | |
| SCHEMBL27540352 | 0.74 | MDM4 (0.31) | MDM4TP53 | |
| SCHEMBL170049 | 0.74 | GABRA1 (0.47) | ALDH1A1 | |
| SCHEMBL3119880 | 0.74 | CYP1A2 (0.50) | MAPTALDH1A1 | |
| SCHEMBL28747958 | 0.73 | GABRA1 (0.44) | MAPTHDAC8ALDH1A1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935421-A | DESULFURIZE THE HEAVY OIL WITH SODIUM HYDROXIDE TO FORM SODIUM SULFIDE, STRIPPING WITH STEAM TO FORM SODIUM HYDROXIDE AND HYDROGEN SULFIDE; CONTACTING THE PARTIALLY DESULFURIZED HEAVY OIL WITH SODIUM TO PRODUCE A SULFUR-FREE PRODUCT | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| US-5695632-A | HEATING HEAVY OIL WITH AQUEOUS SODIUM HYDROXIDE TO PARTIALLY DESULFURIZE AND FORM SODIUM SULFIDE, REGENERATING SODIUM HYDROXIDE WITH TRANSITION METAL SULFIDE, TREATING OIL WITH SODIUM METAL TO PRODUCE SULFUR-FREE OIL | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1997-12-09 | — | — | US | disclosed |