Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802020 | 0.74 | SLC6A4 (0.40) | QDPR | |
| SCHEMBL8416065 | 0.72 | NOS3 (0.48) | IDO1 | |
| SCHEMBL7817199 | 0.66 | SLC6A4 (0.61) | — | |
| SCHEMBL14024008 | 0.64 | QDPR (0.51) | QDPR | |
| SCHEMBL12732022 | 0.60 | POLB (0.42) | — | |
| SCHEMBL3132304 | 0.60 | HTR2A (0.62) | — | |
| SCHEMBL1177623 | 0.60 | HTR2A (0.62) | — | |
| SCHEMBL3936172 | 0.60 | HTR2A (0.62) | — | |
| SCHEMBL22255705 | 0.58 | CHRNA7 (0.45) | — | |
| SCHEMBL531544 | 0.57 | SLC6A4 (0.47) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863935-A | SYNTHESIS OF INDOLE DERIVATIVES OF HETEROCYCLIC COMPOUNDS FOR TREATMENT OF HEADACHES AND MIGRAINES | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |