Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457153 | 0.85 | ALDH1A1 (0.69) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28345812 | 0.83 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7564139 | 0.83 | PARP1 (0.53) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15255336 | 0.81 | KDM4E (0.59) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5448034 | 0.79 | ALDH1A1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8411208 | 0.78 | PARP1 (0.54) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL626969 | 0.75 | RAD52 (0.55) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31399388 | 0.75 | RAD52 (0.55) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29406087 | 0.75 | RAD52 (0.55) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7566595 | 0.75 | ALDH1A1 (0.69) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |