Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10872221 | 0.99 | GAA (0.53) | GAAMAPTKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7026128 | 0.97 | GAA (0.52) | GAAMAPTKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7026130 | 0.97 | GAA (0.52) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL3314693 | 0.97 | GAA (0.54) | GAAMAPTKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8415161 | 0.96 | GAA (0.51) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL11152353 | 0.96 | GAA (0.53) | GAAMAPTKDM4EALDH1A1MEN1 | |
| Fluoride Ion SCHEMBL11152351 | 0.95 | GAA (0.52) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL11332195 | 0.93 | GAA (0.51) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL11141930 | 0.92 | GAA (0.50) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL8353093 | 0.92 | GAA (0.50) | GAAMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57124728-A | — | — | None | — | — | JP | disclosed |
| JP-57185430-A | — | — | None | — | — | JP | disclosed |
| EP-0546198-B1 | BLACK MATRIX BASE BOARD AND MANUFACTURING METHOD THEREFOR, AND LIQUID CRYSTAL DISPLAY PANEL AND MANUFACTURING METHOD THEREFOR | DAINIPPON PRINTING CO LTD (JP) | 1999-08-18 | — | — | EP | disclosed |
| US-5631753-A | LIGHT SHIELDING LAYER MADE FROM A RESIN LAYER CONTAINING METALLIC PARTICLES | DAI NIPPON PRINTING CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0260899-B1 | Photosensitive resin composition and method for producing fine patterns using the photosensitive resin | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-4579804-A | HYDROPHILIC BINDER CONTAINING METAL DEVELOPING NUCLEI, AND OIL-SOLUBLE DEVELOPMENT INHIBITOR | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1986-04-01 | — | — | US | disclosed |
| JP-S57185430-A | HEAT-DEVELOPABLE DIAZO COPYING MATERIAL | RICOH CO LTD | 1982-11-15 | — | — | JP | disclosed |
| JP-S57124728-A | TWO-COMPONENT TYPE DIAZO COPYING MATERIAL | RICOH CO LTD | 1982-08-03 | — | — | JP | disclosed |