Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581049 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL1732395 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8578456 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8579599 | 0.83 | SKP2 (0.50) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL10804584 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8578501 | 0.82 | SKP2 (0.45) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL31179939 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL9321941 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8004946 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 | |
| SCHEMBL8578409 | 0.81 | THRB (0.49) | ALDH1A1SMN1; SMN2TEAD4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914354-A | POLYIMIDE PRECURSOR, TERTIARY AMINE, PHOTOPOLYMERIZATION INITIATOR, SENSITIZER; THICK FILMS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5744203-A | POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |