Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17730126 | 0.84 | IDO1 (0.37) | IDO1ACACBARKMOCYP3A4 | |
| SCHEMBL17730123 | 0.84 | IDO1 (0.37) | IDO1ACACBARKMOCYP3A4 | |
| SCHEMBL28607286 | 0.83 | ACACB (0.40) | IDO1ACACBARKMO | |
| SCHEMBL29524880 | 0.83 | ACACB (0.40) | IDO1ACACBARKMO | |
| SCHEMBL17730020 | 0.80 | IDO1 (0.42) | IDO1ACACBARKMO | |
| SCHEMBL17730021 | 0.80 | IDO1 (0.42) | IDO1ACACBARKMO | |
| SCHEMBL8415224 | 0.76 | MAPT (0.39) | IDO1AR | |
| SCHEMBL8415227 | 0.76 | MAPT (0.39) | IDO1AR | |
| SCHEMBL8705388 | 0.74 | S1PR5 (0.40) | IDO1ARKMO | |
| SCHEMBL8705390 | 0.74 | S1PR5 (0.40) | IDO1ARKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877322-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0719257-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007892-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |