Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27619882 | 0.98 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL28149208 | 0.89 | ALOX15 (0.50) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| Benzamide SCHEMBL27821963 | 0.87 | HSD17B10 (0.53) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL27829573 | 0.86 | KDM4E (0.59) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| Quinaldic Acid SCHEMBL22449357 | 0.84 | MGAM (0.79) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL2175934 | 0.83 | MGAM (0.64) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL20572033 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL163181 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL13781685 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| Quinaldic Acid SCHEMBL27607370 | 0.82 | MGAM (0.77) | ALDH1A1ALOX15HPGDHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286182-A | Novel oxazolidinone fluoro quinolone derivative and purposes | 李靖 | 2017-10-24 | — | — | CN | claimed |
| CN-102395273-B | Thienopyridine derivatives for the treatment and prevention of dengue virus infection | SIGA TECHNOLOGIES INC | 2015-05-20 | — | — | CN | claimed |
| US-8598175-B2 | Heteroarylamide pyrimidone derivatives | SANOFI (FR) | 2013-12-03 | — | — | US | claimed |
| US-8592437-B2 | Heteroarylamide pyrimidone compounds | SANOFI (FR) | 2013-11-26 | — | — | US | claimed |
| CN-101903339-B | Substituted N-phenyl-bipyrrolidine carboxamides and their therapeutic use | SANOFI AVENTIS | 2012-06-27 | — | — | CN | claimed |
| US-8198287-B2 | Substituted heteroaryl pyridopyrimidone derivatives | SANOFI-AVENTIS (FR) | 2012-06-12 | — | — | US | claimed |
| CN-102395273-A | Thienopyridine derivatives for the treatment and prevention of dengue virus infection | SIGA TECHNOLOGIES INC | 2012-03-28 | — | — | CN | claimed |
| CN-101563328-B | substituted heteroaryl Pyridopyrimidinone derivatives | SANOFI AVENTIS | 2012-03-14 | — | — | CN | claimed |
| CN-101679306-B | Heteroaryl amide substituted pyrimidone derivatives for the treatment of neurodegenerative diseases | SANOFI-AVENTIS (FR) | 2011-12-28 | — | — | CN | claimed |
| CN-102083827-A | Thiazolidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-06-01 | — | — | CN | claimed |
| EP-0621788-A4 | HEMOREGULATORY PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0725651-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1995011693-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0621788-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-02 | — | — | EP | claimed |
| CN-1077960-A | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1993-11-03 | — | — | CN | claimed |
| WO-1993013789-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |
| EP-0120832-B1 | 4-ALKYLINDOLONAPHTHYRIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OMNICHEM Société anonyme (BE) | 1987-04-29 | — | — | EP | claimed |
| EP-0120832-A1 | 4-Alkylindolonaphthyridines and pharmaceutical compositions containing them | OMNICHEM Société anonyme (BE) | 1984-10-03 | — | — | EP | claimed |