Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361815 | 0.86 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1BACE1MAPTKDM4E | |
| SCHEMBL8415573 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1BACE1MAPTKDM4E | |
| SCHEMBL8415313 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1BACE1MAPTKDM4E | |
| SCHEMBL7643085 | 0.78 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL28338105 | 0.77 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1BACE1MAPTKDM4E | |
| SCHEMBL17236308 | 0.77 | MAPT (0.47) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL7595655 | 0.77 | KMT2A (0.45) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10425633 | 0.76 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1BACE1MAPTKDM4E | |
| SCHEMBL13182636 | 0.75 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL22587845 | 0.73 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1BACE1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002020-B1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | AMERSHAM PLC (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6458966-B1 | Dye intermediate and method | NYCOMED AMERSHAM PLC (GB) | 2002-10-01 | — | — | US | disclosed |
| EP-1002020-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | Nycomed Amersham plc (GB) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007793-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | NYCOMED AMERSHAM PLC (GB) | 1999-02-18 | — | — | WO | disclosed |