Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718577 | 0.78 | RXFP1 (0.49) | SMN1; SMN2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL8414074 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1TAS2R14HPGDHSD17B10 | |
| SCHEMBL18422725 | 0.74 | KDM4E (0.50) | POLBKDM4ETP53ALDH1A1GRIN2D | |
| SCHEMBL8413913 | 0.73 | GRIA2 (0.51) | KDM4EALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11358865 | 0.73 | TAS2R14 (0.61) | POLBKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11351333 | 0.73 | TAS2R14 (0.61) | POLBKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL3247255 | 0.73 | RXFP1 (0.42) | SMN1; SMN2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL11361353 | 0.72 | TAS2R14 (0.59) | POLBKDM4EALDH1A1GRIN2DGRIN3B | |
| Potassium SCHEMBL11361366 | 0.72 | TAS2R14 (0.59) | POLBKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11358859 | 0.72 | TAS2R14 (0.59) | POLBKDM4EALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |
| EP-0759910-A1 | ACID AMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | EGIS GYOGYSZERGYAR RT. (HU) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031443-A1 | ACID AMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 1995-11-23 | — | — | WO | disclosed |