Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415912 | 1.00 | ESR2 (0.44) | ESR2DRD2IDO1ESR1CYP2C9 | |
| SCHEMBL8415874 | 0.85 | ESR2 (0.42) | ESR2DRD2ESR1CYP2C9CYP3A4 | |
| SCHEMBL8415951 | 0.85 | ESR2 (0.42) | ESR2DRD2ESR1CYP2C9CYP3A4 | |
| SCHEMBL8033905 | 0.84 | HTR3A (0.47) | DRD2CYP2C9HTR3ALSSMEN1 | |
| SCHEMBL8418654 | 0.83 | HTR2C (0.49) | ESR2DRD2IDO1ESR1CYP2C9 | |
| SCHEMBL8418656 | 0.83 | HTR2C (0.49) | ESR2DRD2IDO1ESR1CYP2C9 | |
| SCHEMBL8417332 | 0.81 | ESR2 (0.40) | ESR2ESR1CYP2C9CYP3A4MEN1 | |
| SCHEMBL8418649 | 0.81 | ESR2 (0.36) | ESR2ESR1CYP2C9CYP3A4 | |
| SCHEMBL8418650 | 0.81 | ESR2 (0.36) | ESR2ESR1CYP2C9CYP3A4 | |
| SCHEMBL8417333 | 0.81 | ESR2 (0.40) | ESR2ESR1CYP2C9CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |