Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418650 | 1.00 | ESR2 (0.36) | ESR2OPRL1CCR2HTR2AHTR2C | |
| SCHEMBL8036699 | 0.86 | HTR2A (0.38) | CCR2HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL8417346 | 0.85 | ESR2 (0.32) | ESR2OPRL1 | |
| SCHEMBL8417344 | 0.85 | ESR2 (0.32) | ESR2OPRL1 | |
| SCHEMBL8419351 | 0.84 | OPRL1 (0.33) | ESR2OPRL1 | |
| SCHEMBL8419353 | 0.84 | OPRL1 (0.33) | ESR2OPRL1 | |
| SCHEMBL8977371 | 0.83 | USP5 (0.34) | CCR2HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL8415874 | 0.83 | ESR2 (0.42) | ESR2OPRL1HTR2ACYP2C9ESR1 | |
| SCHEMBL8977367 | 0.83 | USP5 (0.34) | CCR2HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL8977362 | 0.83 | USP5 (0.34) | CCR2HTR2AHTR2CHTR2BUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |