Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415956 | 1.00 | GAA (0.40) | GAAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2265394 | 0.83 | KDM4E (0.35) | METAP1MEN1KMT2AKDM4E | |
| SCHEMBL7169967 | 0.82 | SMYD3 (0.40) | GAAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2586406 | 0.81 | GAA (0.43) | GAATP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2586404 | 0.81 | GAA (0.43) | GAATP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL1722156 | 0.78 | GAA (0.44) | GAAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL1722155 | 0.78 | GAA (0.44) | GAAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7368625 | 0.78 | EPHX2 (0.31) | METAP1SMYD3 | |
| SCHEMBL7419066 | 0.77 | EPHX2 (0.35) | ALDH1A1MEN1KMT2ASMYD3 | |
| SCHEMBL9056470 | 0.77 | EPHX2 (0.35) | ALDH1A1MEN1KMT2ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |