Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303774 | 0.79 | MAPK1 (0.39) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL18574577 | 0.79 | LMNA (0.39) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL28773419 | 0.79 | HTR2B (0.39) | MYCHTR2BLMNATP53CYP1A2 | |
| SCHEMBL25171318 | 0.79 | LMNA (0.54) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL70993 | 0.79 | LMNA (0.54) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL29370508 | 0.79 | LMNA (0.54) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL29246531 | 0.78 | HTR2A (0.40) | HTR2BLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL7873616 | 0.76 | MYC (0.40) | MYCHTR2BLMNANR3C1MEN1 | |
| SCHEMBL2804918 | 0.75 | SCN8A (0.38) | LMNATP53MAPK1NR3C1MEN1 | |
| SCHEMBL7529078 | 0.75 | LMNA (0.36) | HTR2BLMNATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627440-B1 | Metallocenes containing 9-substituted fluorenyl compounds and use of the metallocenes | PHILLIPS PETROLEUM CO (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5610247-A | Unbridged metallocenes of 9-substituted fluorenyl compounds and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0627440-A1 | 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |