SCHEMBL7529078

SCHEMBL7529078

BrC(Br)c1cccc2c1-c1ccccc1C2c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR2B P41595 1/20 0.36
ADRA2C P18825 1/20 0.33
PTGS2 P35354 1/20 0.33
HRH1 P35367 1/20 0.33
HTR3A P46098 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP19A1 P11511 1/20 0.33
NR3C1 P04150 1/20 0.33
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GID4 Q8IVV7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19303774 0.77 MAPK1 (0.39) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL8416167 0.75 MYC (0.42) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL28187238 0.75 ALDH1A1 (0.43) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL18574577 0.74 LMNA (0.39) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL25171318 0.73 LMNA (0.54) LMNATP53CYP1A2CYP3A4MAPT
Benzene SCHEMBL27791155 0.73 LMNA (0.54) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL29370508 0.73 LMNA (0.54) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL70993 0.73 LMNA (0.54) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL29246531 0.69 HTR2A (0.40) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL25775421 0.68 TSHR (0.46) LMNAMAPTNR3C1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020061420-A1 Electroluminescent polymer having fluorene pendant and electroluminescent device using the same SAMSUNG SDI CO., LTD. 2002-05-23 US claimed