Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YES1 | P07947 | 2/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | JAK3 | P52333 | 2/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804260 | 0.91 | YES1 (0.69) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL8804492 | 0.90 | YES1 (0.54) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL9055521 | 0.90 | YES1 (0.81) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL9054761 | 0.90 | YES1 (0.83) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL8804976 | 0.89 | YES1 (0.58) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL8805590 | 0.88 | YES1 (0.55) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL8807702 | 0.88 | KMT2A (0.64) | YES1KDRJAK3CYP19A1RXFP1 | |
| SCHEMBL8805799 | 0.88 | YES1 (0.74) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL8805785 | 0.88 | YES1 (0.59) | YES1KDRJAK3TUBB4ATUBB | |
| SCHEMBL25994791 | 0.87 | IDO1 (0.56) | YES1KDRJAK3TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | claimed |
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |