Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | YES1 | P07947 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 2/20 | 0.53 |
| ▸ | FNTB | P49356 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055555 | 0.89 | GAA (0.65) | KMT2AMEN1ALDH1A1CYP19A1RXFP1 | |
| SCHEMBL8416372 | 0.88 | YES1 (0.67) | KMT2AMEN1ALDH1A1CYP19A1YES1 | |
| SCHEMBL8805985 | 0.86 | TP53 (0.57) | KMT2AMEN1ALDH1A1CYP19A1RXFP1 | |
| SCHEMBL9056948 | 0.81 | POLB (0.53) | KMT2AMEN1ALDH1A1CYP19A1YES1 | |
| SCHEMBL9054761 | 0.80 | YES1 (0.83) | KMT2AMEN1ALDH1A1CYP19A1YES1 | |
| SCHEMBL1233547 | 0.80 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1CYP19A1RXFP1 | |
| SCHEMBL7552365 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1RXFP1POLB | |
| SCHEMBL8804260 | 0.79 | YES1 (0.69) | KMT2AMEN1ALDH1A1CYP19A1YES1 | |
| SCHEMBL8805799 | 0.79 | YES1 (0.74) | KMT2AMEN1ALDH1A1CYP19A1YES1 | |
| SCHEMBL1233342 | 0.79 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |