Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YES1 | P07947 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | JAK3 | P52333 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ICMT | O60725 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.49 |
| ▸ | FNTB | P49356 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416372 | 0.89 | YES1 (0.67) | YES1KDRJAK3CYP19A1ALDH1A1 | |
| SCHEMBL8804260 | 0.88 | YES1 (0.69) | YES1KDRJAK3CYP19A1LMNA | |
| SCHEMBL8805590 | 0.88 | YES1 (0.55) | YES1KDRJAK3LMNAALDH1A1 | |
| SCHEMBL8806145 | 0.87 | YES1 (0.55) | YES1KDRJAK3LMNAALDH1A1 | |
| SCHEMBL8804492 | 0.83 | YES1 (0.54) | YES1KDRJAK3CYP19A1ICMT | |
| SCHEMBL9055521 | 0.83 | YES1 (0.81) | YES1KDRJAK3CYP19A1LMNA | |
| SCHEMBL8806207 | 0.83 | YES1 (0.57) | YES1KDRJAK3CYP19A1LMNA | |
| SCHEMBL8806556 | 0.82 | YES1 (0.64) | YES1KDRJAK3LMNAALDH1A1 | |
| SCHEMBL24480047 | 0.81 | LMNA (0.56) | YES1KDRJAK3CYP19A1MAPK1 | |
| SCHEMBL8805785 | 0.81 | YES1 (0.59) | YES1KDRJAK3ICMTTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |