Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678897 | 0.83 | HTR6 (1.00) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7835971 | 0.82 | HTR6 (0.83) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL8054947 | 0.82 | MAPT (1.00) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7835135 | 0.78 | HTR6 (1.00) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7826353 | 0.77 | HTR6 (0.78) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7834367 | 0.77 | HTR6 (0.78) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7833565 | 0.77 | HTR6 (0.78) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7832815 | 0.77 | L3MBTL1 (0.74) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7837390 | 0.77 | HTR6 (0.78) | HTR6MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7834630 | 0.76 | HTR6 (0.76) | HTR6MAPTALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939451-A | INDOL-4-YL-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |