Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417827 | 0.93 | MAPT (0.47) | ITGB1ITGA4MMEACEACE2 | |
| SCHEMBL10950960 | 0.83 | ITGB1 (0.44) | ITGB1ITGA4MMEACEACE2 | |
| SCHEMBL4576379 | 0.83 | PPARG (0.35) | MMEACEACE2POLBMAPK1 | |
| SCHEMBL10950963 | 0.83 | ITGB1 (0.44) | ITGB1ITGA4MMEACEACE2 | |
| SCHEMBL4576383 | 0.83 | PPARG (0.35) | MMEACEACE2POLBMAPK1 | |
| SCHEMBL13262189 | 0.82 | ASAH1 (0.35) | ITGB1ITGA4ASAH1 | |
| SCHEMBL31676720 | 0.82 | MAPT (0.38) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL13589971 | 0.80 | ITGB1 (0.44) | ITGB1ITGA4ACETGFBR1POLB | |
| SCHEMBL9554833 | 0.79 | LMNA (0.51) | POLBMAPK1FOLH1ALOX15SMN1; SMN2 | |
| SCHEMBL11414215 | 0.79 | LMNA (0.51) | POLBMAPK1FOLH1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889050-A | IMMUNOMODULATOR | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |