SCHEMBL841661

SCHEMBL841661

CCO[Si](C)(OCC)C(Cl)(CC)c1ccc(C(Cl)(Cl)Cl)cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840962 0.85
SCHEMBL841036 0.84 TSHR (0.32) TSHR
SCHEMBL840908 0.83
SCHEMBL1580199 0.75
SCHEMBL841647 0.68
SCHEMBL841034 0.68 TSHR (0.39) TSHR
SCHEMBL840813 0.67
SCHEMBL926430 0.67 TSHR (0.31) TSHR
SCHEMBL926429 0.67 LMNA (0.31) TSHR
SCHEMBL841793 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP claimed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US claimed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US claimed
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP disclosed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US disclosed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US disclosed